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PKC Recombinant Rabbit mAb

Cat No.: ARM2023
Size:
Product Name: PKC Recombinant Rabbit mAb
Cat No.: ARM2023
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Monoclonal
recommended dilution: WB,IP
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human PKC
calculated molecular weight: 78 kDa
observed molecular weight: 78 kDa
genbank accession number: P05129
gene id (ncbi): 5578
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AAG6; PKCA; PRKACA; PKC-alpha
category: Primary Ab
concentration: 1mg/ml
background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]