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RAP1A/B Recombinant Rabbit mAb

Cat No.: ARM2014
Size:
Product Name: RAP1A/B Recombinant Rabbit mAb
Cat No.: ARM2014
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC,IP
clonality: Monoclonal
recommended dilution: WB,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human RAP1A/B
calculated molecular weight: 21 kDa
observed molecular weight: 21 kDa
genbank accession number: P61224
gene id (ncbi): 5906
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]