Zonula occludens protein 3 Recombinant Rabbit mAb
Cat No.: ARM1977
Size：
| Product Name: | Zonula occludens protein 3 Recombinant Rabbit mAb |
| Cat No.: | ARM1977 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB |
| clonality: | Monoclonal |
| recommended dilution: | WB |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Zonula occludens protein 3 |
| calculated molecular weight: | 101 kDa |
| observed molecular weight: | 140 kDa |
| genbank accession number: | O95049 |
| gene id (ncbi): | 27134 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ZO3; ZO-3 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012] |