AMPK gamma 1 Recombinant Rabbit mAb
Cat No.: ARM1954
Size：
| Product Name: | AMPK gamma 1 Recombinant Rabbit mAb |
| Cat No.: | ARM1954 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,FC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,FC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human AMPK gamma 1 |
| calculated molecular weight: | 38 kDa |
| observed molecular weight: | 38 kDa |
| genbank accession number: | P54619 |
| gene id (ncbi): | 5571 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | AMPKG |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |