SAFB Recombinant Rabbit mAb
Cat No.: ARM1953
Size：
| Product Name: | SAFB Recombinant Rabbit mAb |
| Cat No.: | ARM1953 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human SAFB |
| calculated molecular weight: | 103 kDa |
| observed molecular weight: | 150 kDa |
| genbank accession number: | Q15424 |
| gene id (ncbi): | 6294 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HAP; HET; SAF-B; SAFB1; SAB-B1; SAF-B1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a --transcriptosome complex-- in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011] |