PON2 Recombinant Rabbit mAb
Cat No.: ARM1949
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Product Name: | PON2 Recombinant Rabbit mAb |
Cat No.: | ARM1949 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,IP |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human PON2 |
calculated molecular weight: | 39 kDa |
observed molecular weight: | 40-42 kDa |
genbank accession number: | Q15165 |
gene id (ncbi): | 5445 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | A-esterase 2 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |