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RENT1 Recombinant Rabbit mAb

Cat No.: ARM1819
Size:
Product Name: RENT1 Recombinant Rabbit mAb
Cat No.: ARM1819
source: Rabbit
reactivity: Human, Mouse
applications: WB,IHC,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human RENT1
calculated molecular weight: 124 kDa
observed molecular weight: 124 kDa
genbank accession number: Q92900
gene id (ncbi): 5976
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HUPF1; NORF1; RENT1; smg-2; pNORF1
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]