ETAA1 Recombinant Rabbit mAb
Cat No.: ARM1817
| Product Name: | ETAA1 Recombinant Rabbit mAb |
| Cat No.: | ARM1817 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Monoclonal |
| recommended dilution: | WB |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human ETAA1 |
| calculated molecular weight: | 103 kDa |
| observed molecular weight: | 103 kDa |
| genbank accession number: | Q9NY74 |
| gene id (ncbi): | 54465 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ETAA16 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717). |
