Smac/Diablo Rabbit pAb
Cat No.: APA1317
Size:
Product Name: | Smac/Diablo Rabbit pAb |
Cat No.: | APA1317 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20-1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20-1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Smac/Diablo |
calculated molecular weight: | 27 kDa |
observed molecular weight: | 21 kDa |
genbank accession number: | Q9NR28 |
gene id (ncbi): | 56616 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | SMAC; DFNA64 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |