VEGF Receptor 2 Rabbit pAb
Cat No.: APA1311
Size:
Product Name: | VEGF Receptor 2 Rabbit pAb |
Cat No.: | APA1311 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human VEGF Receptor 2 |
calculated molecular weight: | 152 kDa |
observed molecular weight: | 230,210 kDa |
genbank accession number: | P35968 |
gene id (ncbi): | 3791 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | FLK1; CD309; VEGFR; VEGFR2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] |