NF2/Merlin Rabbit pAb
Cat No.: APA1291
Size：
| Product Name: | NF2/Merlin Rabbit pAb |
| Cat No.: | APA1291 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:5000-1:100000 IP: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human NF2/Merlin |
| calculated molecular weight: | 70 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | P35240 |
| gene id (ncbi): | 4771 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ACN; SCH; BANF |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008] |