HSPA2 Rabbit pAb
Cat No.: APA1275
Size：
| Product Name: | HSPA2 Rabbit pAb |
| Cat No.: | APA1275 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human HSPA2 |
| calculated molecular weight: | 70 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | P54652 |
| gene id (ncbi): | 3306 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HSP70-2; HSP70-3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. |