COX1/Cyclooxygenase 1 Rabbit pAb
Cat No.: APA1267
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| Product Name: | COX1/Cyclooxygenase 1 Rabbit pAb |
| Cat No.: | APA1267 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC/IF: 1:20-1:100 FC: 1:20 IP: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human COX1/Cyclooxygenase 1 |
| calculated molecular weight: | 69 kDa |
| observed molecular weight: | 69 kDa |
| genbank accession number: | P23219 |
| gene id (ncbi): | 5742 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |