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ApoER2 Rabbit pAb

Cat No.: APA1259
Size:
Product Name: ApoER2 Rabbit pAb
Cat No.: APA1259
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IP: 1:20-1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human ApoER2
calculated molecular weight: 106 kDa
observed molecular weight: 130,106 kDa
genbank accession number: Q14114
gene id (ncbi): 7804
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MCI1; LRP-8; APOER2; HSZ75190
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]