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RAB7 Rabbit pAb

Cat No.: APA1221
Size:
Product Name: RAB7 Rabbit pAb
Cat No.: APA1221
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:50
ICC/IF: 1:20-1:100
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human RAB7
calculated molecular weight: 24 kDa
observed molecular weight: 24 kDa
genbank accession number: P51149
gene id (ncbi): 7879
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: RAB7; PRO2706
category: Primary Ab
concentration: 0.5mg/ml
background: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]