Junctional Adhesion Molecule 1 Rabbit pAb
Cat No.: APA1216
Size：
| Product Name: | Junctional Adhesion Molecule 1 Rabbit pAb |
| Cat No.: | APA1216 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000 IHC: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Junctional Adhesion Molecule 1 |
| calculated molecular weight: | 33 kDa |
| observed molecular weight: | 33 kDa |
| genbank accession number: | Q9Y624 |
| gene id (ncbi): | 50848 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5-- alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] |