HDAC8 Rabbit pAb
Cat No.: APA1184
Size:
Product Name: | HDAC8 Rabbit pAb |
Cat No.: | APA1184 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human HDAC8 |
calculated molecular weight: | 42 kDa |
observed molecular weight: | 42 kDa |
genbank accession number: | Q9BY41 |
gene id (ncbi): | 55869 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |