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HDAC8 Rabbit pAb

Cat No.: APA1184
Size:
Product Name: HDAC8 Rabbit pAb
Cat No.: APA1184
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human HDAC8
calculated molecular weight: 42 kDa
observed molecular weight: 42 kDa
genbank accession number: Q9BY41
gene id (ncbi): 55869
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1
category: Primary Ab
concentration: 0.5mg/ml
background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]