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Coilin Rabbit pAb

Cat No.: APA1180
Size:
Product Name: Coilin Rabbit pAb
Cat No.: APA1180
source: Rabbit
reactivity: Human
applications: WB,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Coilin
calculated molecular weight: 63 kDa
observed molecular weight: 80 kDa
genbank accession number: P38432
gene id (ncbi): 8161
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CLN80; p80-coilin
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]