TMEM173 Rabbit pAb
Cat No.: APA1173
Size：
| Product Name: | TMEM173 Rabbit pAb |
| Cat No.: | APA1173 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human TMEM173 |
| calculated molecular weight: | 42 kDa |
| observed molecular weight: | 40 kDa |
| genbank accession number: | Q86WV6 |
| gene id (ncbi): | 340061 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |