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CD86 Rabbit pAb

Cat No.: APA1172
Size:
Product Name: CD86 Rabbit pAb
Cat No.: APA1172
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:100
ICC/IF: 1:100
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human CD86
calculated molecular weight: 38 kDa
observed molecular weight: 75 kDa
genbank accession number: P42081
gene id (ncbi): 942
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: B70; B7-2; B7.2; LAB72; CD28LG2
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]