CD86 Rabbit pAb
Cat No.: APA1172
Size:
Product Name: | CD86 Rabbit pAb |
Cat No.: | APA1172 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CD86 |
calculated molecular weight: | 38 kDa |
observed molecular weight: | 75 kDa |
genbank accession number: | P42081 |
gene id (ncbi): | 942 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | B70; B7-2; B7.2; LAB72; CD28LG2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |