STIP1 Rabbit pAb
Cat No.: APA1154
Size:
Product Name: | STIP1 Rabbit pAb |
Cat No.: | APA1154 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:20 FC: 1:50 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human STIP1 |
calculated molecular weight: | 63 kDa |
observed molecular weight: | 63 kDa |
genbank accession number: | P31948 |
gene id (ncbi): | 10963 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009] |