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STIP1 Rabbit pAb

Cat No.: APA1154
Size:
Product Name: STIP1 Rabbit pAb
Cat No.: APA1154
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
IHC: 1:20
ICC/IF: 1:20
FC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human STIP1
calculated molecular weight: 63 kDa
observed molecular weight: 63 kDa
genbank accession number: P31948
gene id (ncbi): 10963
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521
category: Primary Ab
concentration: 0.5mg/ml
background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]