Staufen Rabbit pAb
Cat No.: APA1147
Size：
| Product Name: | Staufen Rabbit pAb |
| Cat No.: | APA1147 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:50 ICC/IF: 1:100 FC: 1:200-1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Staufen |
| calculated molecular weight: | 63 kDa |
| observed molecular weight: | 63 kDa |
| genbank accession number: | O95793 |
| gene id (ncbi): | 6780 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | STAU; PPP1R150 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5--UTR. [provided by RefSeq, Jul 2008] |