Integrin alpha 5 Rabbit pAb
Cat No.: APA1145
Size:
Product Name: | Integrin alpha 5 Rabbit pAb |
Cat No.: | APA1145 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:50 ICC/IF: 1:100 FC: 1:20-1:100 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Integrin alpha 5 |
calculated molecular weight: | 115 kDa |
observed molecular weight: | 150 kDa |
genbank accession number: | P08648 |
gene id (ncbi): | 3678 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | FNRA; CD49e; VLA-5; VLA5A |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] |