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MMP3 Rabbit pAb

Cat No.: APA1134
Size:
Product Name: MMP3 Rabbit pAb
Cat No.: APA1134
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human MMP3
calculated molecular weight: 54 kDa
observed molecular weight: 54 kDa
genbank accession number: P08254
gene id (ncbi): 4314
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
category: Primary Ab
concentration: 0.5mg/ml
background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP--s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]