APE1 Rabbit pAb
Cat No.: APA1087
Size：
| Product Name: | APE1 Rabbit pAb |
| Cat No.: | APA1087 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human APE1 |
| calculated molecular weight: | 36 kDa |
| observed molecular weight: | 36 kDa |
| genbank accession number: | P27695 |
| gene id (ncbi): | 328 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | APE; APX; APE1; APEN; APEX; HAP1; REF1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5-- to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008] |