Transglutaminase 2 Rabbit pAb
Cat No.: APA1085
Size:
Product Name: | Transglutaminase 2 Rabbit pAb |
Cat No.: | APA1085 |
source: | Rabbit |
reactivity: | Human, Mouse |
applications: | WB,IHC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 IHC: 1:50 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Transglutaminase 2 |
calculated molecular weight: | 77 kDa |
observed molecular weight: | 77 kDa |
genbank accession number: | P21980 |
gene id (ncbi): | 7052 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | TGC; TG(C) |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |