HP1 gamma Rabbit pAb
Cat No.: APA1082
Size：
| Product Name: | HP1 gamma Rabbit pAb |
| Cat No.: | APA1082 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 FC: 1:20-1:100 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human HP1 gamma |
| calculated molecular weight: | 21 kDa |
| observed molecular weight: | 21 kDa |
| genbank accession number: | Q13185 |
| gene id (ncbi): | 11335 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HECH; HP1-GAMMA; HP1Hs-gamma |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5-- UTR, have been found for this gene.[provided by RefSeq, Mar 2011] |