NFkB p100 Rabbit pAb
Cat No.: APA1077
Size：
| Product Name: | NFkB p100 Rabbit pAb |
| Cat No.: | APA1077 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,ICC/IF,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 ICC/IF: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human NFkB p100 |
| calculated molecular weight: | 97 kDa |
| observed molecular weight: | 100 kDa |
| genbank accession number: | Q00653 |
| gene id (ncbi): | 4791 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |