MMP12 Rabbit pAb
Cat No.: APA1030
Size:
Product Name: | MMP12 Rabbit pAb |
Cat No.: | APA1030 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human MMP12 |
calculated molecular weight: | 54 kDa |
observed molecular weight: | 54,45 kDa |
genbank accession number: | P39900 |
gene id (ncbi): | 4321 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ME; HME; MME; MMP-12 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |