c-Rel Rabbit pAb
Cat No.: APA1026
Size:
Product Name: | c-Rel Rabbit pAb |
Cat No.: | APA1026 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human c-Rel |
calculated molecular weight: | 69 kDa |
observed molecular weight: | 78 kDa |
genbank accession number: | Q04864 |
gene id (ncbi): | 5966 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | C-Rel |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin--s lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] |