cGAS Rabbit pAb
								Cat No.: APA1024
															
							 
							| Product Name: | cGAS Rabbit pAb | 
| Cat No.: | APA1024 | 
| source: | Rabbit | 
| reactivity: | Mouse | 
| applications: | WB, IP | 
| clonality: | Polyclonal | 
| recommended dilution: | WB: 1:1000 IP: 1:20 | 
| format: | Liquid | 
| isotype: | IgG | 
| immunogen: | Recombinant protein of mouse cGAS | 
| calculated molecular weight: | 58 kDa | 
| observed molecular weight: | 58 kDa | 
| genbank accession number: | Q8C6L5 | 
| gene id (ncbi): | 101559 | 
| purification method: | Affinity Purification | 
| conjugate: | Un-conjugated | 
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. | 
| synonyms: | Mb21d1; E330016A19Rik | 
| category: | Primary Ab | 
| concentration: | 0.5mg/ml | 
| background: | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] | 
 
				