Ephrin receptor A2 Rabbit pAb
Cat No.: APA1017
Size：
| Product Name: | Ephrin receptor A2 Rabbit pAb |
| Cat No.: | APA1017 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Ephrin receptor A2 |
| calculated molecular weight: | 109 kDa |
| observed molecular weight: | 125 kDa |
| genbank accession number: | Q03145 |
| gene id (ncbi): | 13836 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Eck; Myk2; Sek2; Sek-2; AW545284 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 signaling pathway. |