TLR2 Rabbit pAb
Cat No.: APA1014
Size：
| Product Name: | TLR2 Rabbit pAb |
| Cat No.: | APA1014 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TLR2 |
| calculated molecular weight: | 90 kDa |
| observed molecular weight: | 90 kDa |
| genbank accession number: | O60603 |
| gene id (ncbi): | 7097 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TIL4; CD282 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host--s inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |