Apolipoprotein E Rabbit pAb
Cat No.: APA5254
Size:
Product Name: | Apolipoprotein E Rabbit pAb |
Cat No.: | APA5254 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Apolipoprotein E |
calculated molecular weight: | 36 kDa |
observed molecular weight: | 36 kDa |
genbank accession number: | P02649 |
gene id (ncbi): | 348 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | AD2; LPG; APO-E; ApoE4; LDLCQ5 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016] |