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HNF-4-alpha Rabbit pAb

Cat No.: APA5237
Size:
Product Name: HNF-4-alpha Rabbit pAb
Cat No.: APA5237
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human HNF-4-alpha
calculated molecular weight: 53 kDa
observed molecular weight: 53 kDa
genbank accession number: P41235
gene id (ncbi): 3172
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]