HNF-4-alpha Rabbit pAb
Cat No.: APA5237
Size:
Product Name: | HNF-4-alpha Rabbit pAb |
Cat No.: | APA5237 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human HNF-4-alpha |
calculated molecular weight: | 53 kDa |
observed molecular weight: | 53 kDa |
genbank accession number: | P41235 |
gene id (ncbi): | 3172 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] |