TFE3 Rabbit pAb
Cat No.: APA5233
Size：
| Product Name: | TFE3 Rabbit pAb |
| Cat No.: | APA5233 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:50-1:200 ICC/IF: 1:20-1:50 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human TFE3 |
| calculated molecular weight: | 62 kDa |
| observed molecular weight: | |
| genbank accession number: | P19532 |
| gene id (ncbi): | 7030 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TFEA; RCCP2; RCCX1; bHLHe33 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |