Cytokeratin 8 Rabbit pAb
Cat No.: APA5227
Size：
| Product Name: | Cytokeratin 8 Rabbit pAb |
| Cat No.: | APA5227 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,IHC,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:5000-1:20000 IHC: 1:20 ICC/IF: 1:20-1:100 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Cytokeratin 8 |
| calculated molecular weight: | 54 kDa |
| observed molecular weight: | 54 kDa |
| genbank accession number: | P05787 |
| gene id (ncbi): | 3856 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | K8; KO; CK8; CK-8; CYK8; K2C8; CARD2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |