• Drop us a line for any questions: info@assayvector.com

Estrogen Receptor alpha Rabbit pAb

Cat No.: APA5226
Size:
Product Name: Estrogen Receptor alpha Rabbit pAb
Cat No.: APA5226
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC,IP,ChIP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
IP: 1:20
ChIP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Estrogen Receptor alpha
calculated molecular weight: 66 kDa
observed molecular weight: 66 kDa
genbank accession number: P03372
gene id (ncbi): 2099
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ER; ESR; Era; ESRA; ESTRR; NR3A1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]