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Glutamine Synthetase Rabbit pAb

Cat No.: APA5212
Size:
Product Name: Glutamine Synthetase Rabbit pAb
Cat No.: APA5212
source: Rabbit
reactivity: Human, Mouse
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:500
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Glutamine Synthetase
calculated molecular weight: 42 kDa
observed molecular weight: 42 kDa
genbank accession number: P15104
gene id (ncbi): 2752
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: GS; GLNS; PIG43; PIG59
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]