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Pax2 Rabbit pAb

Cat No.: APA5198
Size:
Product Name: Pax2 Rabbit pAb
Cat No.: APA5198
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Pax2
calculated molecular weight: 45 kDa
observed molecular weight: 45 kDa
genbank accession number: Q02962
gene id (ncbi): 5076
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: FSGS7; PAPRS
category: Primary Ab
concentration: 0.5mg/ml
background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]