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FTO Rabbit pAb

Cat No.: APA5195
Size:
Product Name: FTO Rabbit pAb
Cat No.: APA5195
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
IHC: 1:50
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human FTO
calculated molecular weight: 58 kDa
observed molecular weight: 58 kDa
genbank accession number: Q9C0B1
gene id (ncbi): 79068
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: GDFD; ALKBH9; BMIQ14
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]