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GDF15 Rabbit pAb

Cat No.: APA5177
Size:
Product Name: GDF15 Rabbit pAb
Cat No.: APA5177
source: Rabbit
reactivity: Human
applications: WB,IHC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human GDF15
calculated molecular weight: 34 kDa
observed molecular weight: 35,13 kDa
genbank accession number: Q99988
gene id (ncbi): 9518
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]