eIF4EBP1 Rabbit pAb
Cat No.: APA5174
Size：
| Product Name: | eIF4EBP1 Rabbit pAb |
| Cat No.: | APA5174 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human eIF4EBP1 |
| calculated molecular weight: | 12 kDa |
| observed molecular weight: | 15-20 kDa |
| genbank accession number: | Q13541 |
| gene id (ncbi): | 1978 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | BP-1; 4EBP1; 4E-BP1; PHAS-I |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5-- end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |