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Granzyme B Rabbit pAb

Cat No.: APA5170
Size:
Product Name: Granzyme B Rabbit pAb
Cat No.: APA5170
source: Rabbit
reactivity: Human
applications: IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: IHC: 1:50
ICC/IF: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Granzyme B
calculated molecular weight: 28 kDa
observed molecular weight:
genbank accession number: P10144
gene id (ncbi): 3002
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]