CD8 Rabbit pAb
Cat No.: APA5169
Size：
| Product Name: | CD8 Rabbit pAb |
| Cat No.: | APA5169 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:20-1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human CD8 |
| calculated molecular weight: | 26 kDa |
| observed molecular weight: | |
| genbank accession number: | P01732 |
| gene id (ncbi): | 925 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CD8; MAL; p32; Leu2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |