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GCN2 Rabbit pAb

Cat No.: APA5157
Size:
Product Name: GCN2 Rabbit pAb
Cat No.: APA5157
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:100
ICC/IF: 1:50-1:200
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human GCN2
calculated molecular weight: 187 kDa
observed molecular weight: 187 kDa
genbank accession number: Q9P2K8
gene id (ncbi): 440275
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: GCN2; PVOD2
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]