Collagen XVII Rabbit pAb
Cat No.: APA5140
Size：
| Product Name: | Collagen XVII Rabbit pAb |
| Cat No.: | APA5140 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:20 ICC/IF: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Collagen XVII |
| calculated molecular weight: | 150 kDa |
| observed molecular weight: | |
| genbank accession number: | Q9UMD9 |
| gene id (ncbi): | 1308 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008] |