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Syndecan-1 Rabbit pAb

Cat No.: APA5119
Size:
Product Name: Syndecan-1 Rabbit pAb
Cat No.: APA5119
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:50-1:200
ICC/IF: 1:50
FC: 1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Syndecan-1
calculated molecular weight: 33 kDa
observed molecular weight: 33 kDa
genbank accession number: P18827
gene id (ncbi): 6382
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: SDC; CD138; SYND1; syndecan
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]