Syndecan-1 Rabbit pAb
Cat No.: APA5119
Size:
Product Name: | Syndecan-1 Rabbit pAb |
Cat No.: | APA5119 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:50-1:200 ICC/IF: 1:50 FC: 1:100 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Syndecan-1 |
calculated molecular weight: | 33 kDa |
observed molecular weight: | 33 kDa |
genbank accession number: | P18827 |
gene id (ncbi): | 6382 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | SDC; CD138; SYND1; syndecan |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] |