Rho Rabbit pAb
Cat No.: APA5091
Size:
Product Name: | Rho Rabbit pAb |
Cat No.: | APA5091 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:2000 IHC: 1:20-1:100 ICC/IF: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Rho |
calculated molecular weight: | 22 kDa |
observed molecular weight: | 22 kDa |
genbank accession number: | P08134 |
gene id (ncbi): | 389 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | H9; ARH9; ARHC; RHOH9 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |