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MMP9 Rabbit pAb

Cat No.: APA5073
Size:
Product Name: MMP9 Rabbit pAb
Cat No.: APA5073
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20-1:500
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human MMP9
calculated molecular weight: 78 kDa
observed molecular weight: 78 kDa
genbank accession number: P14780
gene id (ncbi): 4318
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: GELB; CLG4B; MMP-9; MANDP2
category: Primary Ab
concentration: 0.5mg/ml
background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP--s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]